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Xi'an Julong Bio-Tech Co., Ltd.

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Anti Diabetes 99% Cas105816-04-4 Nateglinide Powder

CAS NO.105816-04-4

  • FOB Price: USD: 0.70-1.50 /Gram Get Latest Price
  • Min.Order: 100 Gram
  • Payment Terms: L/C|D/A|D/P|T/T||MoneyGram|Other
  • Available Specifications:

    99%(100-499)Gram99%(500-999)Gram99%(1000--1)Gram

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Product Details

Keywords

Quick Details

  • ProName: Anti Diabetes 99% Cas105816-04-4 Nateg...
  • CasNo: 105816-04-4
  • Molecular Formula: C19H27NO3
  • Appearance: White Powder
  • Application: Anti Diabetes, Anti Diabetes
  • DeliveryTime: Have stock can shipping anytime
  • PackAge: 25G~1KG/FOIL BAG
  • Port: Any port in China
  • ProductionCapacity: /
  • Purity: 99%
  • Storage: Cool Dry Place
  • Transportation: By DHL/ By Fedex/ By EMS/By TNT/By Sea...
  • LimitNum: 100 Gram

Superiority

Details

Products Description
Anti Diabetes 99% Cas105816-04-4 Nateglinide Powder
Product Name:
Nateglinide
CAS RN.:
105816-04-4
Molecular Weight:
317.4226
Molecular Formula:
C19H27NO3
Density:
1.105g/cm3
Melting Point(℃):
137-141℃
Boiling Point(℃):
527.578°C at 760 mmHg
Flash Point(℃):
272.869°C
Introduction:
Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Nateglinide is an amino acid derivative that induces an early insulin response to meals decreasing postprandial blood glucose levels. It should only be taken with meals and meal-time doses should be skipped with any skipped meal.

Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. The average weight gain caused by meglitinides appears to be lower than that caused by sulfonylureas and insulin and appears to occur only in those naïve to oral antidiabetic agents. Due to their mechanism of action, meglitinides may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since their action is dependent on the presence of glucose. In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control.

Meglitinides appear to be more effective at lowering postprandial blood glucose than metformin, sulfonylureas and
thiazolidinediones. Nateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major metabolites possess less activity than the parent compound. One minor metabolite, the isoprene, has the same potency as its parent compound.
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Application & Function:

1.Nateglinide is used for the treatment of the form of diabetes mellitus that appears most frequently in adulthood -- known as type 2 or non-insulin-dependent diabetes -- that cannot be managed by exercise and control of diet alone.

2.Nateglinide may be added to diet and exercise to manage the disease, or it may be combined with metformin when diet, exercise, and either drug alone cannot provide adequate control of blood sugar.
Specification
ITEMS
SPECIFICATIONS
RESULTS
Appearance
White crystalline powder or colorless crystals
Passes
Identification
Accord With BP2007
Passes
Assay
98.5%~101.0%
99.97%
Melting point
75°C~78°C
77°C
Optical rotation
-0.05°~+0.05°
0.00°
Heavy metals
≤ 0.001%
<0.001%
Related substances
Impurity B
≤ 0.3%
Passes
Any other impurity
≤ 0.3%
Passes
Total of all impurities apart from impurity B
≤ 0.7%
Passes
Impurity F
≤ 0.1%
Not detected
Sulphated ash
≤ 0.1%
0.02%
Appearance of solution
Accord With BP2007
Passes
Conclusion: COMPLY WITH BP2007
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Our Review:
FAQ
1. who are we?
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

4. why should you buy from us not from other suppliers?
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian
Company Profile
Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development
Why Choose Us
1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 
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