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Xi'an Julong Bio-Tech Co., Ltd.

Country: China (Mainland)

Business Type:Trading Company

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Supply 99% Setipiprant Anti Hair Loss Setipiprant

CAS NO.866460-33-5

  • FOB Price: USD: 6.50-8.50 /Gram Get Latest Price
  • Min.Order: 10 Gram
  • Payment Terms: L/C|D/A|D/P|T/T||MoneyGram|Other
  • Available Specifications:

    99%(10-49)Gram99%(50-99)Gram99%(100--1)Gram

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Product Details

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Quick Details

  • ProName: Supply 99% Setipiprant Anti Hair Loss ...
  • CasNo: 866460-33-5
  • Molecular Formula: C24H19FN2O3
  • Appearance: White Powder
  • Application: Anti Hair Loss, Anti Hair Loss
  • DeliveryTime: Have stock can shipping anytime
  • PackAge: 25G~1KG/FOIL BAG
  • Port: Any port in China
  • ProductionCapacity: /
  • Purity: 99%
  • Storage: Cool Dry Place
  • Transportation: By DHL/ By Fedex/ By EMS/By TNT/By Sea...
  • LimitNum: 10 Gram

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Products Description
Supply 99% Setipiprant Anti Hair Loss Setipiprant
Product Name:
Setipiprant
Aaasy:
99%
CAS:
866460-33-5
Appearance:
White fine powder
Testing Method: 
HPLC
Function: 
Anti-hair loss
Introduction:
Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.

However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.

A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.
Real Shot
Application & Function:
1.For maximum effect, the solution should be in contact with the scalp for hours before being washed out. It does not seem capable of reducing DHT or the enzyme responsible for its accumulation around the hair follicle, 5-aliha reductase.

2.Which are the main causes of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT already accumlated around the follicle has its expected effect, and the follicle usually shrinks again and eventually dies.

3.Setipiprant powder can promote hair regrowth,slow or stop hair loss and treat high blood pressure.Setipiprant needs to be applied once or twice daily for hair to be maintained

Applicaiton/Dosage

Scalp hair loss Acting through DP2, PGD2 can inhibit hair growth, suggesting that this receptor is a potential target for bald treatment. A phase 2A study to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo in 18 to 49 year old males with androgenetic.Setipiprant proved to be well-tolerated and reasonably effective in reducing allergen-induced airway responses in asthmatic patient clinical trials.
Specification
Items
Requirements
Results
Appearance:
White powder
White powder
Identification
A. IR
B. HPLC
Conforms
Loss on drying
≤0.5%
0.19%
Identification A
IR spectrum corresponds to the reference chloramphenicol standard
Conforms
Related Substance
Individual impurity ≤0.5%
Total impurity ≤1.5%
0.06%
0.09%
Heavy metal
Pb :
Cadmium(Cd) :
As :
Hg:
≤ 10ppm
<1 ppm
<0.5 ppm
<10ppm
< 1 ppm
<10ppm
Conforms
0.3ppm
Conforms
Negative
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872365-14-5
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OC000459
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Finasteride
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Our Review:
FAQ
1. who are we?
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

4. why should you buy from us not from other suppliers?
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery；
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian
Company Profile
Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development
Why Choose Us
1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 
Package & Delivery
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