Keywords

• CAS 877399-52-5 Crizotinib
• 99% Crizotinib Powder
• Crizotinib Powder

Quick Details

• ProName: Supply 99% CAS 877399-52-5 Crizotinib ...
• CasNo: 877399-52-5
• Molecular Formula: C21H22Cl2FN5O
• Appearance: White Powder
• Application: For Bodybuilding Muscle Growth Custom...
• DeliveryTime: Within 3 Days After Payment
• PackAge: Foil Bag / Drum / Bottle
• Port: Shanghai
• ProductionCapacity: 1000 Kilogram/Day
• Purity: 99%
• Storage: Well-Closed, Store in cool and dry are...
• Transportation: Well-Closed, Store in cool and dry are...
• LimitNum: 50 Gram
• Related Substances: ≥98%
• Residue on Ignition: ≤0.1%
• Heavy Metal: ≤10ppm
• Valid Period: 24Months
• Product Name: Crizotinib
• MF: C21H22Cl2FN5O
• CAS: 877399-52-5
• Appearance: White Powder
• Grade: Medicine Grade
• Application: Medicine Grade
• Certificate: COA ISO9001 GMP
• Form: Capsules, Liquid, Powder
• Transport Package: Foil Bag / Drum / Bottle
• Purity: 99%
• Shelf Life: 2 Years
• Storage: Cool and Dry Place

Superiority

1. Who are we
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),

Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),

Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates.

4. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement ,

the quality and technical content can reach the advance level in China .

Our products are sold well in China as well as in more than 20 countries.

5. What services can we provide
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian.

6.We promise our customer following items

Support product customization:

We can provide OEM&ODM , Because we have a professional design team.

Reasonable price:
We provide high quality products with competitive price in china,

Low MOQ:
No worry about the low moq, our moq is 1 gram or lower.

Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.

Super-good quality
We have strict quality control system .Good reputation in Market , And have the Third party test report is available.

Details

What's CAS 877399-52-5 Crizotinib Powder

Crizotinib (trade name Xalkori,) is an anti-cancer drug acting as an ALK (anaplastic lymphoma kinase) and ROS1

(c-ros oncogene 1) inhibitor, approved for treatment of some non-small cell lung carcinoma (NSCLC) in the US and

some other countries, and undergoing clinical trials testing its safety and efficacy inanaplastic large cell lymphoma,

neuroblastoma, and other advanced solid tumors in both adults and children.

Crizotinib has an aminopyridine structure, and functions as a protein kinase inhibitor by competitive binding within the

ATP-binding pocket of target kinases. About 4% of patients with non-small cell lung carcinoma have a chromosomal

rearrangement that generates a fusion genebetween EML4 ('echinoderm microtubule-associated protein-like 4') andALK

('anaplastic lymphoma kinase'), which results in constitutivekinase activity that contributes to carcinogenesis and seems

to drive the malignant phenotype.

The kinase activity of the fusion protein is inhibited by crizotinib. Patients with this gene fusion are typically younger

non-smokers who do not have mutations in either theepidermal growth factor receptor gene (EGFR) or in the K-Ras

gene.The number of new cases of ALK-fusion NSLC is about 9,000 per year in the U.S. and about 45,000 worldwide.

Application & Function 

Treating certain types of lung cancer. It may also be used for other conditions as determined by your doctor.
Crizotinib is a tyrosine kinase inhibitor. It works by preventing the growth of cancer cells.

Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved in the

oncogenesis of a number of other histological forms of malignant neoplasms.

Crizotinib is currently thought to exert its effects through modulation of the growth, migration, and invasion of malignant

cells.Other studies suggest that crizotinib might also act via inhibition of angiogenesis in malignant tumors.

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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