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Home>>Products>>GMP Factory Supply raw material powder Domperidone for antiemetic treatment

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Xi'an Julong Bio-Tech Co., Ltd.

Country: China (Mainland)

Business Type:Trading Company

Ms.Victoria

Tel: +008618049624045

Mobile: 18049624045

Tel: +008618049624045

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URL: http://LookChem.com

Province/state: Shaan xi

City: xi'an

Street: Xi'an

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GMP Factory Supply raw material powder Domperidone for antiemetic treatment

  • FOB Price: USD: 20.00-100.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C|D/A|D/P|T/T|||Other
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Product Details

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Quick Details

  • ProName: GMP Factory Supply raw material powder...
  • Appearance: White powder
  • DeliveryTime: Have stock can shipping anytime
  • Port: Any port in China
  • ProductionCapacity: /
  • Storage: Cool Dry Place
  • Transportation: By DHL/ By Fedex/ By EMS/By TNT/By Sea...
  • LimitNum: 1 Kilogram

Superiority

Details

Product Description
Product name
Domperidone
English alias
6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one; Domperidonum
CAS No
57808-66-9
Molecular formula
C22H24ClN5O
Molecular weight
425.911
Exact Mass
425.162
PSA
78.82
LogP
3.2911
Appearance and traits
white powder
Density
1.341 g/cm3
Melting point
242.5oC
Stability
Stable, incompatible with strong oxidants
Storage conditions
sealed and stored

Domperidone is a benzimidazole compound that has strong stomach-stimulating and antiemetic effects, can strengthen the lower esophageal sphincter tension, prevent gastric-esophageal reflux, enhance gastric motility, promote gastric emptying, and coordinate the stomach with the twelve-finger Intestinal exercise, inhibition of nausea, vomiting, and effective prevention of bile reflux, does not affect the secretion of gastric juice.

Function

Function :

1. Domperidone is used for the treatment of gastroparesis (especially diabetic gastro-light gastroparesis), which can eliminate the symptoms of gastric retention and shorten the gastric emptying time; patients with moderate to moderate functional dyspepsia (FD) It can completely eliminate or significantly reduce symptoms such as abdominal distention, epigastric pain, belching, early satiety, nausea, and vomiting after meals.

2. Reflux gastroesophageal and esophageal diseases: Domperidone has a significant effect on reflux gastritis, but it is not very satisfactory for the efficacy of reflux esophagitis.

3. Peptic ulcer: Domperidone can be used as an adjunctive treatment for peptic ulcers (mainly gastric ulcers) to eliminate antral retention.

4. Nausea and vomiting caused by various reasons: (1) Nausea and vomiting after surgery and gynecological surgery. (2) Gastrointestinal symptoms caused by antiparkinsonian drugs (such as Benzhexol, Hyoscyamine, etc.) and adverse reactions caused by dopamine receptor agonists (such as levodopa and bromocriptine). (3) Vomiting caused by cytotoxic drugs (such as anticancer drugs). However, vomiting caused by potent nausea such as nitrogen mustard is only effective in less severe periods. (4) Vomiting caused by diseases of the digestive system (gastritis, hepatitis, pancreatitis, etc.). (5) Nausea and vomiting caused by other diseases and examinations and treatment measures, such as migraine, dysmenorrhea, craniocerebral trauma, uremia, hemodialysis, gastroscopy, and radiation therapy. (6) Acute and persistent vomiting of children due to various reasons, such as infection, postprandial (including reflux and vomiting) and so on.

5. Promote postpartum lactation


Application :

Gastrointestinal problems

There is some evidence that domperidone has antiemetic activity. Domperidone is used, together with metoclopramide, cyclizine, and 5HT3 receptor antagonists (such as granisetron) in the treatment of nausea and vomiting.

It can be used in patients with Parkinson's disease because, unlike metoclopramide, domperidone does not cross the blood–brain barrier.

Domperidone has also been found effective in the treatment of gastroparesis, a stomach motility condition, and for paediatric gastroesophageal reflux (infant vomiting).

Packing & Delivery
Our Company

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development


FAQ

Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or Paypal or Escrow(Alibaba).

Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q4:What's your MOQ?
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Q5: How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6:Is there a discount?
A:Different quantity has different discount.

Q7: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss

Certifications
Our Service

1. All inquiries will be replied within 12 hours.


2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

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