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Ms.Amber Ms.Florence Ms.Lisa Ms.EllenCAS NO.1260141-27-2
Supply High Purity Vonoprazan Fumarate TAK-438 | ||||||
Product name | Vonoprazan fumarate |
CAS NO. | 1260141-27-2 |
Synonyms | Vonoprazan |
Category | Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals. |
Standard | purity:>99% |
Appearance | Vonoprazan fumarate powder |
Shelf life | 2 years |
Usage | Vonoprazan fumarate shows strong and sustainable acid secretion inhibitory effects as well as demonstrate efficacy in early termination by inhibiting the binding of potassium ion (K+) to H+, K+-ATPase (proton pump) in the final step of gastric acid secretion in gastric parietal cells. |
Storage | Vonoprazan fumarate should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Vonorazan Fumarate is a new oral anti-gastric acid drug developed by Takeda Pharmaceutical Co-operation with Takazu Pharmaceutical Co-operation.
TEST | SPECIFICATION | RESULT | |
Appearance | White to off-white crystals | White crystals | |
Identification | 1-HNMR: Consistent with the standard | Conforms | |
IR: The IR absorption spectrum of the sample must be concordant with test Standard. | Conforms | ||
HPLC: The HPLC spectrum of the sample must be concordant with the standard substance. | Conforms | ||
Residue on ignition | NMT 0.2% | 0.02% | |
Water | NMT 2.0% | 0.06% | |
Heavy Metals | NMT 20ppm | 5ppm | |
Related Substance | Impurity A: NMT 0.2% | 0.07% | |
Impurity B: NMT 0.15% | 0.03% | ||
Impurity C: NMT 0.15% | 0.07% | ||
Any other impurity: NMT 0.10% | N.D. | ||
Total impurities: NMT 1.0% | 0.17% | ||
Residual Solvents | Methanol: NMT 0.3% | N.D. | |
Ethanol: NMT 0.5% | N.D. | ||
Ethyl acetate: NMT 0.5% | N.D. | ||
Assay(By HPLC) | 98.0%~102% | 99.84% | |
Storage | Store in a tightly closed container in a cool and dry place, below | ||
Conclusion | Confirm to enterprise standard | ||
Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.
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