Xi'an Julong Bio-Tech Co., Ltd.
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Country: 
China (Mainland)
Business Type:Trading Company
Tel: +008618049624045
Tel: +008615877690239
Tel: +0086-18792996027
Tel: +008618049624045
Tel: +008618291367393
Tel: +8618629260427
Tel: +008617802922472
Tel: +008618729964529
Mobile: 18049624045
Tel: +008618049624045
Fax:
URL: http://LookChem.com
Province/state: Shaan xi
City: xi'an
Street: Xi'an
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Ms.Amber Ms.Florence Ms.Lisa Ms.EllenCAS NO.135463-81-9
99%(1-24)Kilogram99%(25-99)Kilogram99%(100-500)Kilogram
Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
3. OEM/ODM Available.
4. Reasonable & competitive price, fast lead time.
5. Sample is available for your evaluation & Formulation development.
6. Faster delivery:Sample order in stock and 3-7 days for bulk production.
7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
8. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Product name :Coluracetam MKC-231
CAS : 135463-81-9
Molecular Formula : C19H23N3O3
Molecular Weight : 341.40
Boiling Point:634.1°C at 760 mmHg °C
Appearance: white crystalline powder
Specification: 99% by HPLC
Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.
Benefit:
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.
Function & Application:
Coluracetam is a nootropic agent of the racetam family. It may have potential use in prevention and treatment of ischemicretinopathy and retinal and optic nerve injury. Coluracetam has also been shown to reverse the loss of choline acetyltransferase production in the medial septal nucleus of rats exposed to phencyclidine (pcp), and is considered a potential therapeutic drug for schizophrenia.
The mode of action for coluracetam is still being researched, but initial studies indicate that this nootropic interacts with the process of high affinity choline uptake (HACU). This improves a neuron’s ability to create the neurotransmitter acetylcholine, which is involved with memory formation.
Dosage:
Due to the potency of coluracetam, the dosage is relatively low. Animal research indicates that an oral dose of 300 – 3,000 mcg/kg of bodyweight is useful, which translates to around 3.2-32.7mg overall for a human of 150 lbs. Research for human consumption is scarce, but anecdotal evidence suggests 20mg as a good starting dosage for coluracetam. Sublingual can make the impact of coluracetam far more potent.
Specification
| Item | Specifications | Results |
| Assay(HPLC) | 98.0%~102.0% | 98.9% |
| Appearance | Off-white crystalline powder | Complies |
| Identification | IR | Complies |
| Melting point | 156.0~160.0℃ | 157.0~158.0℃ |
| Loss on drying | ≤0.5% | 0.11% |
| Residue on ignition | ≤0.1% | 0.06% |
| Related substance | ≤1.0% | 0.75% |
| Heavy metals | ≤10ppm | Complies |
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By Express |
By Air |
By Sea |
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Suitable for under 50kg |
Suitable for more than 50kg |
Suitable for more than 500kg |
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Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
3. OEM/ODM Available.
4. Reasonable & competitive price, fast lead time.
5. Sample is available for your evaluation & Formulation development.
6. Faster delivery:Sample order in stock and 3-7 days for bulk production.
7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
8. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests
Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
