Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Trading Company
Tel: +008618049624045
Tel: +008615877690239
Tel: +0086-18792996027
Tel: +008618049624045
Tel: +008618291367393
Tel: +8618629260427
Tel: +008617802922472
Tel: +008618729964529
Mobile: 18049624045
Tel: +008618049624045
Fax:
URL: http://LookChem.com
Province/state: Shaan xi
City: xi'an
Street: Xi'an
MaxCard:
CAS NO.157115-85-0
1(1-10)Kilogram1(10-50)Kilogram1(50-100)Kilogram
Noopept (GVS111) factory 157115-85-0 Wholesaler reasonable price
NooglutilexhibitspharmacologicallysignificantcompetitionwithaselectiveagonistofAMPAreceptors([G-3H]Ro48-8587)forthereceptorbindingsites(withIC50=6.4+/-0.2microM),whilethecompetitionofnoopeptforthesereceptorbindingsiteswaslowerbyanorderofmagnitude(IC50=80+/-5.6microM).GVS111significantlyincreasedneuronalsurvivalafterH(2)O(2)treatmentdisplayingadosedependentneuroprotectiveactivityfrom10nMto100microM,andanIC(50)valueof1.21+/-0.07microM.GVS111inhibitedtheaccumulationofintracellularfreeradicalsandlipidperoxidationdamageinneuronstreatedwithH(2)O(2)orFeSO(4),suggestinganantioxidantmechanismofaction
N-Phenylacetyl-L-prolylglycineethylester(GVS-111)administeredintravenouslyatadoseof0.5mg/kg/day,forthefirsttime1hafterischaemiclesionandthenfor9post-operativedays,withthelastadministration15minbeforetesting,attenuatedthedeficit[3].GVS-111itselfwasnotfoundinratbrain1hafter5mg/kgi.p.administrationuptolimitofdetection(LOD)underhighperformanceliquidchromatography(HPLC)conditions.Themostpronouncedantiinflammatoryeffectofdipeptidewasobservedonthemodelofadjuvantarthritisinrats,wherethedrugadministeredover25daysinadailydoseof0.5mg/kg(i.m.)or5mg/kg(p.o.)significantlyreducedthechronicimmuneinflammation(onthe12thday,by94.0and74.1%,respectively)
our strengths:
1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line)
2: Various payment items accepted (Btc; MoneyGram; WU)
3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging)
4: Efficient delivery (3-10 DAYS fast delivery service )
5: Good reputation (we have been in this industry for years, earned great trust from our clients from allover the world)
6: Huge Capacity (We have plenty manufacture centers, each day can produce tons of various products.)
7: The most competitive price (manufacture and produce by our own factories)