Xi'an Julong Bio-Tech Co., Ltd.
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Country: 
China (Mainland)
Business Type:Trading Company
Tel: +008618049624045
Tel: +008615877690239
Tel: +0086-18792996027
Tel: +008618049624045
Tel: +008618291367393
Tel: +8618629260427
Tel: +008617802922472
Tel: +008618729964529
Mobile: 18049624045
Tel: +008618049624045
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URL: http://LookChem.com
Province/state: Shaan xi
City: xi'an
Street: Xi'an
MaxCard:
Ms.Amber Ms.Florence Ms.Lisa Ms.EllenCAS NO.23593-75-1
Powder(50-300)KilogramPowder(300-700)Kilogram
1. Who are we
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),
Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),
Eastern Europe(00.00%). There are total about 11-50 people in our office.
2. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates.
4. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement ,
the quality and technical content can reach the advance level in China .
Our products are sold well in China as well as in more than 20 countries.
5. What services can we provide
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian.
6.We promise our customer following items
Support product customization:
We can provide OEM&ODM , Because we have a professional design team.
Reasonable price:
We provide high quality products with competitive price in china,
Low MOQ:
No worry about the low moq, our moq is 1 gram or lower.
Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.
Super-good quality
We have strict quality control system .Good reputation in Market , And have the Third party test report is available.
What's CAS 23593-75-1 Clotrimazole Powder
| Product Name | Clotrimazole |
| CAS NO. | 23593-75-1 |
| MOQ | 1 kg |
| Other Name | Clotrimazole crystalline,Clotrimazole powder |
| Molecular Formular | C22H17ClN2 |
| Molecular Weight | 344.837 |
| Appearance | White crystalline powder |
Clotrimazole is an derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor.
Target: Antifungal; CYPClotrimazole is an antifungal medication commonly used in the treatment of fungal
infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm.
It is also used to treat athlete's foot and jock itch.It is commonly available as an over-the-counter substance
in various dosage forms, such as a cream, and also (especially in the case of ear infection) as a combination
medicine. It is also available as a troche or throat lozenge (prescription only). For ear infection, it is often
applied in liquid form, as ear drops.The antimycotic drug clotrimazole inhibits the function of the gastric
H,K-ATPase in a manner similar to that observed for the Na,K-ATPase. Because of the high hydrophobicity
of the compound, the interaction between clotrimazole and the ion pump occurs at the membrane domain
in the apolar core of the membrane. The enzymatic activity was inhibited with a half-saturating concentration
of 5.2 microM. Various partial reactions of the pump cycle were analyzed with the electrochromic styryl
dye RH421 that has been widely used to study the transport mechanism of P-type ATPases.
Application & Function
1. Clotrimazole inhibits ergosterol biosynthesis by interfering with cytochrome P450 activity;
2. Damage the fungal cell membrane and change its permeability to avoid the leakage of important substances
in the cell;
3. It can also inhibit the biosynthesis of triglycerides and phospholipids in fungi;
4. The product can also inhibit the activities of oxidation and peroxidase, cause excessive accumulation
of peroxides in cells and cause degeneration and necrosis of fungal subcellular structure.
5. Clotrimazole has broad-spectrum antifungal activity. It has good antibacterial activity against dermatophytes,
Trichophyton, Aspergillus, chromomyces, Cryptococcus and Candida. It also has certain antibacterial activity
against Sporothrix schenckii, Blastomyces dermatitis, coccidiospora and histoplasmosis.
|
ITEMS |
SPECIFICATION EP6/USP32 |
RESULTS |
|
CHARACTERS(PH.EUR.) |
A WHITE OR ALMOST WHITE,CRYSTALLINE POWDER |
COMPLIES |
|
SOLUBILITY(PH.EUR.) |
PRACTICALLY INSOLUBLE IN WATER,SPARINGLY SOLUBLE IN ACETONE AND IN ALCOHOL,SLIGHTLY IN METHYLENE CHLORIDE |
COMPLIES |
|
IDENTIFICATION |
||
|
A.IR-SPECTRUM(PH.EUR) |
MEETS THE REQUIREMENT |
COMPLIES |
|
B.TLC(PH.EUR) |
MEETS THE REQUIREMENT |
COMPLIES |
|
A.IR-SPECTRUM(USP) |
MEETS THE REQUIREMENT |
COMPLIES |
|
B.UV ABSORPTION(USP) |
MEETS THE REQUIREMENT |
COMPLIES |
|
SPECIFIC OPTICAL ROTATION |
||
|
(PH.EUR) |
BETWEEN+150°AND +156° |
+152.1° |
|
(USP) |
BETWEEN+150°AND +156° |
+153.3° |
|
LOSS ON DRYING |
||
|
(PH.EUR) |
NOT MORE THAN 1.0% |
0.04% |
|
(USP) |
NOT MORE THAN 1.0% |
0.05% |
|
RESIDUE ON IGNITION(USP) |
NEGLIGIBLE,FROM 100MG |
COMPLIES |
|
RELATED SUBSTANCES(PH.EUR) |
||
|
ANY INDIVIDUAL IMPURITY |
NOT MORE THAN 0.5% |
0.30% |
|
SUM OF IMPURITIES |
NOT MORE THAN 1.5% |
1.24% |
|
CHROMATOGRAPHIC PURITY(USP) |
||
|
ANY INDIVIDUAL IMPURITY |
NOT MORE THAN 0.5% |
0.28% |
|
SUM OF IMPURITIES |
NOT MORE THAN 2.0% |
1.25% |
|
ASSAY |
||
|
UV ABSORPTION(PH.EUR.) |
BETWEEN 97.0% AND 103.0% |
100.70% |
|
HPLC(USP) |
BETWEEN 97.0% AND 102.0% |
98.70% |
|
RESIDUAL SOLVENT(IN-HOUSE) |
||
|
METHANOL |
NOT MORE THAN 500PPM |
NOT DETECT OUT |
|
ETHANOL |
NOT MORE THAN 2000PPM |
455PPM |
|
METHYLENE CHLORIDE |
NOT MORE THAN 600PPM |
NOT DETECT OUT |
|
CONCLUSION:THE PRODUCT CONFORMS TO PH.EUR.6/USP34 |
||
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & Formulation development.
7. Faster delivery:Sample order in stock and 3-7 days for bulk production.
8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder
9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Delivery & Payment Terms
Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged
in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials
and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability
of product quality from all aspects. The company has a complete sales service system, the products are exported to countries
all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,
constantly strict requirements, set goals, and implement win-win development.
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