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CAS NO.528-43-8
99%(1-50)Kilogram99%(51-100)Kilogram
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Xi'an Julong Bio-Tech Co., Ltd.
Magnolol tan to white fine powder of Magnolia Bark Extract, Chinese Magnolia officinalis (MagnoliaofficinalisRehderetWilson) active ingredient in skin antibacterial effect. Has a special, long-lasting muscle relaxation and strong antibacterial effect, inhibit platelet aggregation. The major clinical use as an antibacterial, antifungal.
[English name] Magnolol
[Molecular formula and molecular weight] C18H18O2,266.32
[CAS No. 528-43-8]
[Source] Magnoliaceae Magnolia officinalis
[Physical and chemical properties White to tan powder, soluble in benzene, ether, chloroform, ethanol, and insoluble in water. The reaction with methanol solution of ferric chloride, was blue-black, reacted with Millon reagent, now brown precipitate, the reaction among the three phenol solution of hydrochloric acid and benzene are now red precipitate.
Effects on the digestive system
The extract of magnolia officinalis officinalis could inhibit the formation of salt-acid ulcer in mice. Honokiol,
the active ingredient of Magnolol, can inhibit gastric acid secretion and resist ulcer. Magnolol can obviously
fight diarrhea in sensene-leaved mice and promote bile flow in rats, indicating that Magnolol can promote
digestive system as well as wenli medicine. Magnolia officinalis treating food, cold and damp dysentery,
temperature in pain.
Analgesic and anti-inflammatory pharmacological effects
Magnolia officinalis is an aromatic and wet herb with analgesic and anti-inflammatory activities. Magnolia
officinalis ethanol extract 5g/kg and 15g/kg have significant analgesic effects, significantly reduce the increase
of capillary permeability in the abdominal cavity of mice caused by acetic acid, and significantly inhibit the ear
swelling of mice caused by xylene and the paw swelling of mice caused by carrageenin. The experiment shows
that magnolia officinalis has obvious anti-inflammatory and analgesic effects.
Central and peripheral muscle relaxation and antispasmodic effect
Magnolia officinalis is often used for extreme nervous, excited state and cause unknown vibration. Magnolol,
the extract of magnolia officinalis, has the effect of blocking neuromuscular junction and can induce the central
muscle relaxation similar to that of myophenol. And honokiol have sedative and anti-anxiety effects. At ultra-high
doses, beta eucalyptus alcohol and diphenyl ethyl ureide sodium showed stronger effects in preventing
electroconvulsive seizures. It is expected that beta eucalyptus alcohol can be used as a synergistic therapy in
antiepileptic therapy or antiepileptic therapy with diphenyl ethyl ureide sodium.
Pharmaceutical hygiene products and antimicrobial agents
Magnolol, the active component of magnolia officinalis extract, can be used as an antibacterial agent
(gram-negative bacteria and acid-resistant bacteria) and can be used to prevent and treat acne.
Daily chemical wash and care application
Oral hygiene products to fight tooth decay, inhibit tooth decay. The inhibition of Magnolol on NF-cB cells
proved to improve the function of skin immune cells and had anti-inflammatory effect.
Cosmetic applications
The inhibition of Magnolol on NF-cB cells proved to improve the function of skin immune cells and had
anti-inflammatory effect. Magnolol can also be used as an antioxidant and skin whitening agent.
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