Xi'an Julong Bio-Tech Co., Ltd.
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Country: 
China (Mainland)
Business Type:Trading Company
Tel: +008618049624045
Tel: +008615877690239
Tel: +0086-18792996027
Tel: +008618049624045
Tel: +008618291367393
Tel: +8618629260427
Tel: +008617802922472
Tel: +008618729964529
Mobile: 18049624045
Tel: +008618049624045
Fax:
URL: http://LookChem.com
Province/state: Shaan xi
City: xi'an
Street: Xi'an
MaxCard:
Ms.Amber Ms.Florence Ms.Lisa Ms.EllenCAS NO.57808-66-9
Powder(1-100)KilogramPowder(100-500)Kilogram
1. Who are we
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),
Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),
Eastern Europe(00.00%). There are total about 11-50 people in our office.
2. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates.
4. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement ,
the quality and technical content can reach the advance level in China .
Our products are sold well in China as well as in more than 20 countries.
5. What services can we provide
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian.
6.We promise our customer following items
Support product customization:
We can provide OEM&ODM , Because we have a professional design team.
Reasonable price:
We provide high quality products with competitive price in china,
Low MOQ:
No worry about the low moq, our moq is 1 gram or lower.
Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.
Super-good quality
We have strict quality control system .Good reputation in Market , And have the Third party test report is available.
What's Domperidone Powder
| Product Name | Domperidone |
| Cas No | 57808-66-9 |
| Appearance | White Powder |
| MF | C22H24ClN5O2 |
| MW | 425.911 |
Domperidone is a peripherally selective dopamine D2receptor antagonist developed by Janssen
Pharmaceutica that is used as an antiemetic, gastroprokinetic agent, and galactogogue.It may be
administered orally or rectally, and is available in the form of tablets,orally disintegrating tablets
(based on Zydis technology), suspension, and suppositories.The drug is used to relieve nausea and
vomiting; to increase the transit of food through the stomach (by increasinggastrointestinal peristalsis);
and to promote lactation (breast milk production) by release of prolactin.
Application & Function
Nausea and vomiting
There is some evidence that domperidone has antiemetic activity.It is recommended in the Canadian
Headache Society's guidelines for treatment of nausea associated with acute migraine.
Gastroparesis
Gastroparesis is a medical condition characterised by delayed emptying of the stomach when there is no
mechanical gastric outlet obstruction. Its cause is most commonly idiopathic, a diabetic complication or
a result of abdominal surgery. The condition causes nausea, vomiting, fullness after eating, early satiety
(feeling full before the meal is finished), abdominal pain and bloating.
Domperidone may be useful in diabetic and idiopathic gastroparesis.
However, increased rate of gastric emptying induced by drugs like domperidone does not always correlate
(equate) well with relief of symptoms.
Parkinson's disease
Parkinson's disease is a chronic neurological condition where a decrease in dopamine in the brain leads
to rigidity (stiffness of movement), tremor and other symptoms and signs. Poor gastrointestinal function,
nausea and vomiting is a major problem for people with Parkinson's disease because most medications
used to treat Parkinson's disease are given by mouth. These medications, such as levodopa can cause
nausea as a side effect. Furthermore, anti-nausea drugs, such as metoclopramide, which do cross the
blood-brain barrier may worsen theextra-pyramidal symptoms of Parkinson's disease.
Domperidone can be used to relieve gastrointestinal symptoms in Parkinson's disease, because, even
though it blocks dopamine receptors (which would be expected to worsen Parkinson's disease), it does
not cross theblood-brain barrier (the barrier between the blood circulation of the brain and the rest of
the body).In addition to this, domperidone may enhance the bioavailability (effect) of levodopa (one
of the main treatments in Parkinson's disease).
Although these features make domperidone a useful drug in Parkinson's disease, caution is needed
due to thecardiotoxic side effects of domperidone especially when given intravenously, in elderly
people and in high doses (> 30 mg per day). A clinical sign of domperidone's potential toxicity
to the heart is the prolongation (lengthening) of the QT interval (a segment of the heart's electrical
pattern).
Functional dyspepsia
Domperidone may be used in functional dyspepsia in both adults and children
| Items | Requirements | Results |
| Appearance | White to off white powder | White powder |
| Solubility | Practically insoluble in water, soluble in dimethylformamide, | Confirms |
| slightly soluble in ethanol(96%) and in methanol | ||
| Identification | A. M.P. 244~248ºC | 244.5~245.5ºC |
| B. IR should comply | Confirms | |
| C. TLC should comply | Confirms | |
| D. It gives the reaction of non-nitrogen substituted barbiturates. | Confirms | |
| Clarity of solution | The solution is clear and not more intensely colored than | Confirms |
| reference solution Y6 | ||
| Related substance | Total impurities≤0.5% | ≤0.29% |
| Individual impurity≤0.25% | ≤0.18% | |
| Loss on drying | ≤0.5% | 0.07% |
| Sulphated ash | ≤0.1% | ≤0.05% |
| Heavy metal | ≤20ppm | <20ppm |
| Assay | 99.0%~101.0% | 99.49 |
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & Formulation development.
7. Faster delivery:Sample order in stock and 3-7 days for bulk production.
8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder
9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Delivery & Payment Terms
Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged
in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials
and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability
of product quality from all aspects. The company has a complete sales service system, the products are exported to countries
all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,
constantly strict requirements, set goals, and implement win-win development.
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