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Xi'an Julong Bio-Tech Co., Ltd.

Country: China (Mainland)

Business Type:Trading Company

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Pharmaceutical Raw Materials 99% Powder CAS 81409-90-7 Dostinex/Cabergoline

CAS NO.81409-90-7

  • msdsMSDS/COA Download

  • FOB Price: USD: 3.00-5.00 /Gram Get Latest Price
  • Min.Order: 10 Gram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    99%(1-24)Gram99%(25-99)Gram99%(100-500)Gram

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Product Details

Keywords

  • Dostinex
  • Cabergoline
  • 81409-90-7

Quick Details

  • ProName: Pharmaceutical Raw Materials 99% Powde...
  • CasNo: 81409-90-7
  • Molecular Formula: C26H37N5O2
  • Appearance: white powder
  • DeliveryTime: 3-7 days after payment
  • PackAge: 1kg/Bag,25kg/Drum
  • Port: CHINA PORT
  • ProductionCapacity: 5000 Metric Ton/Month
  • Purity: 99.0%
  • Storage: Store in a cool, dry, ventilated place
  • Transportation: By DHL/Fedex/EMS/TNT/Sea/Air
  • LimitNum: 10 Gram
  • Residue on Ignition: Conforms
  • Heavy Metal: Conforms
  • Valid Period: 2 years
  • Grade: Industrial Grade,Pharma Grade
  • Product Name: Dostinex/Cabergoline
  • Appearance: White Powder
  • Shipping Origin: China
  • Shelf Life: 2 Years
  • Storage: Cool Dried Storage
  • Assay: Min 98%
  • Sample: Available
  • Standard: Export Standard
  • Trademark: Julong
  • Specification: 99%min
  • COA: Available
  • Package: 1kg/Bag,25kg/Drum
  • MOQ: 10 Gram
  • Test Method: HPLC UV
  • Grade: Pharmaceutical Grade
  • Origin: China

Superiority

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

Details

Products Description

 

Synonyms:6-allyl-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)ergoline-8-carboxamide;(8-beta)-(2-propenyl);n-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-ergoline-8-carboxamid;(8b)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)- ergoline-8-carboxamide;Cabaser;Dostine
CAS:81409-90-7
MF:C26H37N5O2
MW:451.6
Chemical Properties:White crystalline solid
Assay:99%
Usage:A dopamine D2-receptor agonist.receptor stimulant.
Biological Activity:Selective D 2 -like dopamine receptor agonist (K i values are 0.7, 1.5, 9.0 and 165 nM for D 2 , D 3 , D 4 and D 5 receptors respectively) that also displays high affinity for several serotonin receptor subtypes (K i = 1.2-20.0 nM for 5-HT 1A , 5-HT 1D , 5-HT 2A and 5-HT 2B ). Inhibits secretion of prolactin and grow th horm one and reverses levodopa-induced dyskinesias in Parkinsonian monkeys. 

Cabergoline, an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. Rat studies show cabergoline has a direct inhibitory effect on pituitary lactotroph cells. It is frequently used as a first-line agent in the management of prolactinomas due to its higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine.

    

Application:

1). adjunctive therapy of prolactin-producing pituitary gland tumors (prolactinomas);
3). treatment of uterine fibroids.
4). monotherapy of Parkinson's disease in the early phase;
5). combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson's disease;
6). in some countries also: ablactation and dysfunctions associated with (amenorrhea, oligomenorrhea, anovulation, nonpuerperal mastitis and galactorrhea);
7) Cushing's disease - cabergoline may be used to lower ACTH levels and cause regression of ACTH producing pituitary adenomas;
8) adjunctive therapy of acromegaly, cabergoline has low efficacy in suppressing levels and is highly efficient in suppressing that is present in 20-30% of acromegaly cases;
9).and prolactin are similar structurally and have similar effects in many target tissues, therefore targeting prolactin may help symptoms when hormone secretion can not be sufficiently controlled by other methods

Specification:

Description White Or Practically White Crystalline Powder
Ref. Standard Enterprise Standard
Results Of Analysis Tests
Tests Analysis Standard Results
Melting Point 176~181ºC 176.5~181ºC
Specific Rotation +25°~ +31° +25.9°
Loss On Drying ≤0.5% 0.36%
Assay ≥97% 98.1%
Conclusion Be Conform With Enterprise Standard

 

Package & Delivery

By Express

By Air

By Sea

Suitable for under 50kg
Fast: 3-7 days
High cost
Door to door service,
easy to pick up the goods

Suitable for more than 50kg
Fast: 3-7 days
High cost
Port to port,
professional broker needed

Suitable for more than 500kg
Slow: 7-45 days
Low cost
Port to port,
professional broker needed

 

About us

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

FAQ

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests
Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.

 

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