Keywords

• 99% Setipiprant
• CAS 866460-33-5 Setipiprant
• Hair Loss Treatment Setipiprant

Quick Details

• ProName: Supply 99% Hair Loss Treatment CAS 154...
• CasNo: 866460-33-5
• Molecular Formula: C24H19FN2O3
• Appearance: White Powder
• Application: For Bodybuilding Muscle Growth Custom...
• DeliveryTime: Within 3 Days After Payment
• PackAge: Foil Bag / Drum / Bottle
• Port: Shanghai
• ProductionCapacity: 1000 Kilogram/Day
• Purity: 99%
• Storage: Well-Closed, Store in cool and dry are...
• Transportation: Well-Closed, Store in cool and dry are...
• LimitNum: 10 Gram
• Related Substances: ≥98%
• Residue on Ignition: ≤0.1%
• Heavy Metal: ≤10ppm
• Valid Period: 24Months
• Product Name: Setipiprant
• MF: C24H19FN2O3
• CAS: 866460-33-5
• Appearance: White Powder
• Grade: Medicine Grade
• Application: Hair Loss Treatment
• Certificate: COA ISO9001 GMP
• Form: Capsules, Liquid, Powder
• Transport Package: Foil Bag / Drum / Bottle
• Purity: 99%
• Shelf Life: 2 Years
• Storage: Cool and Dry Place

Superiority

1. Who are we
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),

Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),

Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates.

4. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement ,

the quality and technical content can reach the advance level in China .

Our products are sold well in China as well as in more than 20 countries.

5. What services can we provide
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian.

6.We promise our customer following items

Support product customization:

We can provide OEM&ODM , Because we have a professional design team.

Reasonable price:
We provide high quality products with competitive price in china,

Low MOQ:
No worry about the low moq, our moq is 1 gram or lower.

Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.

Super-good quality
We have strict quality control system .Good reputation in Market , And have the Third party test report is available.

Details

What's Setipiprant Powder ？

Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by

Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2).

It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma,

but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced

airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and

was discontinued from further development in this application.

However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed

at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were

acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness,

with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will

be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side

effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be

conducted fairly quickly.

A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative

to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.

1. Increase cellular proliferation of outer root sheeth cells.

2. Increase hair diameter and hair density.

3. Increase the percentage of hair in the anagen phase.

4. Exert no negative effect on body hormone levels.

5. Provide equivalent or better net growth than Finasteride.
 

Androgenetic alopecia

       This form of hair loss is also called male pattern baldness.It can         
        be also occur in women as well

Telogen Effluvium

This form of hair loss causes the person to loose more than 90% of their hair

Alopecia Areata

This condition can affect people as young as 18.It happens when your immune systerm starts attacking

your hair follocles

Traction Alopecia

This hair loss condition can affect males or Females.It couses portions of your hair to fall out at the edges.

Hairstyles such as pigtails dreadlocks and braids are the cause of this conditon.

Anagen Effluvium

This condition causes shedding during the anagen phase or growth stage.Chemotherapy is the most

common cause.

Prostate enlargement

Dutasteride is occasionally used for treating benign prostatic hyperplasia (BPH); colloquially known as

an "enlarged prostate". It is approved by the Food and Drug Administration (FDA) in the U.S. for this

indication.

Pattern hair loss

Dutasteride is approved for the treatment of male androgenetic alopecia in South Korea at a dosage of

0.5 mg per day.
It has been found in several studies to improve hair growth in men more rapidly and to a greater extent

than 2.5 mg/day finasteride.Dutasteride has also been used off-label in the treatment of female pattern

hair loss.

Prostate cancer

In those who are being regularly screened, 5α-reductase inhibitors such as finasteride and dutasteride

reduce the overall risk of being diagnosed with prostate cancer; however, there is insufficient data to

determine if they have an effect on the risk of death and may increase the chance of more serious cases

Excessive hair growth

Although no reports specific to dutasteride currently exist,5α-reductase inhibitors like finasteride have

been found to be effective in the treatment of hirsutism (excessive facial and/or body hair growth) in

women.In a study of 89 women with hyperandrogenism due to persistent adrenarche syndrome,

finasteride produced a 93% reduction in facial hirsutism and a 73% reduction in bodily hirsutism

after 2 years of treatment.Other studies using finasteride for hirsutism have also found it to be clearly

effective.[2] Dutasteride may be more effective than finasteride for this indication due to the fact that

its inhibition of the 5α-reductase enzyme is comparatively more complete.

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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