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Xi'an Julong Bio-Tech Co., Ltd.

Country: China (Mainland)

Business Type:Trading Company

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Tel: +008618049624045

Mobile: 18049624045

Tel: +008618049624045

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Province/state: Shaan xi

City: xi'an

Street: Xi'an

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USP/ BP cas 1405-97-6 Raw Material Gramicidin A Powder Gramicidin

  • FOB Price: USD: 15.00-30.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C|D/A|D/P|T/T|||Other
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  • ProName: USP/ BP cas 1405-97-6 Raw Material Gra...
  • Appearance: White Powder
  • DeliveryTime: Have stock can shipping anytime
  • Port: Any port in China
  • ProductionCapacity: /
  • Storage: Cool Dry Place
  • Transportation: By DHL/ By Fedex/ By EMS/By TNT/By Sea...
  • LimitNum: 1 Kilogram

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Product Description
Product Name
Gramicidin A 
CAS 
1405-97-6
Molecular Formula
C60H92N12O10
Molecular Weight
456.32
Appearance
White powder 

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is a linear polypeptide antibiotic with a mixture of gramicidin A, B, C, and D. Gramicidin D is a channel-forming ionophore that flip-flops slowly across the membrane and is a known Pgp substrate and surprisingly was found to inhibit Pgp ATPase activity. This inhibition was reversed by other Pgp substrates suggesting a common drug binding site among MDR substrate-type drugs and chemosensitizers

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Function :

Gramicidin A is a lipophilic substance, the two short bacitracin molecules are dimer to the left helix space configuration,constitute a cross-lipid membrane membrane channel to combine and carry a specific cation from the side of the membrane into the channel and then spread to The other side of the membrane, so there is the name of ion antibiotics, so that the cell metabolism can not be normal and inhibited or even death. They have a significant effect on Gram-positive bacteria

The product is white and light yellow crystalline powder. Odorless. Melting point ≥ 229 ℃. Soluble in ethanol, acetic acid,pyridine; slightly soluble in acetone; insoluble in water, ether. Thermal stability, the UV absorption peak of 271,231.5,290.5nm.Not easily digested by protease, but can be acid

Application : 

 
On the Bacillus anthracis, Clostridium perfringens, pneumococcus and golden yellow pus micrococcus and so have a good antibacterial effect.

Take gramicidin A as an example. Because it is a fat-soluble substance, two gramicidins The molecular dimer is in a left-hand helix spatial configuration, forming a channel across the bilayer lipid membrane membrane to bind and carry specific cations from one side of the membrane into the channel and then diffuse to the other side of the membrane, so there is an ion antibiotic. Said, so that cell metabolism can not be normal and suppressed or even died.

They have a significant effect on gram-positive bacteria. It has good antibacterial activity against Bacillus anthris, Clostridiumperfringens, Diplococcus pneumoniae and Micrococcus pyogenes Var. aureus. Only at high concentrations does it have an inhibitory effect on certain gram-negative bacteria.

General ointment formulations for the prevention and treatment of skin purulent disease.

Specification :

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Our Company

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development


FAQ

Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or Paypal or Escrow(Alibaba).

Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q4:What's your MOQ?
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Q5: How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6:Is there a discount?
A:Different quantity has different discount.

Q7: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss

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Our Service

1. All inquiries will be replied within 12 hours.


2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

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