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Xi'an Julong Bio-Tech Co., Ltd.

Country: China (Mainland)

Business Type:Trading Company

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Tel: +008618049624045

Mobile: 18049624045

Tel: +008618049624045

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Province/state: Shaan xi

City: xi'an

Street: Xi'an

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Factory sell High Quality Diabetes Medicine 99% API Nateglinide

CAS NO.105816-04-4

  • FOB Price: USD: 100.00-600.00 /Kilogram Get Latest Price
  • Min.Order: 10 Kilogram
  • Payment Terms: L/C|D/A|D/P|T/T|||Other
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  • ProName: Factory sell High Quality Diabetes Med...
  • CasNo: 105816-04-4
  • Molecular Formula: C19H27NO3
  • Appearance: White powder, White Powder
  • Application: Animal Pharmaceuticals
  • DeliveryTime: Have stock can shipping anytime
  • PackAge: 1kg/bag
  • Port: Any port in China
  • ProductionCapacity: /
  • Purity: 98%min
  • Storage: Cool Dry Place
  • Transportation: By DHL/ By Fedex/ By EMS/By TNT/By Sea...
  • LimitNum: 10 Kilogram

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Product Description
Factory sell High Quality Diabetes Medicine 99% API Nateglinide
Product name
Nateglinide
CAS No.
105816-04-4
MF
C19H27NO3
Boiling Point
527.6°C at 760 mmHg
Appearance
White  powder
Assay
99%
Melting Point
137-141°C
Shelf life
24months
Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It
belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to
stimulate insulin release. Nateglinide is an amino acid derivative that induces an early insulin response to meals decreasing
postprandial blood glucose levels. It should only be taken with meals and meal-time doses should be skipped with any skipped meal.
Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral
effect on weight or cause a slight increase in weight. The average weight gain caused by meglitinides appears to be lower than
that caused by sulfonylureas and insulin and appears to occur only in those naïve to oral antidiabetic agents. Due to their
mechanism of action, meglitinides may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since
their action is dependent on the presence of glucose. In addition to reducing postprandial and fasting blood glucose, meglitnides
have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose
control. Meglitinides appear to be more effective at lowering postprandial blood glucose than metformin, sulfonylureas and
thiazolidinediones. Nateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major
metabolites possess less activity than the parent compound. One minor metabolite, the isoprene, has the same potency as its parent
compound
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Function
1.Nateglinide is used for the treatment of the form of diabetes mellitus that appears most frequently in adulthood -- known as
type 2 or non-insulin-dependent diabetes -- that cannot be managed by exercise and control of diet alone.
2.Nateglinide may be added to diet and exercise to manage the disease, or it may be combined with metformin when diet, exercise,
and either drug alone cannot provide adequate control of blood sugar.
Dose:
Oral, each 90 mg, three times daily, 10 minutes before a meal to take, according to the disease in the future need to gradually
increase the dose to each 120 mg, or as directed.

Application

Those who are allergic to the chemicals, pregnant women, severe infection, severe trauma patients before and after surgery and
diabetic coma and insulin-dependent diabetes patients disabled.
1. severe liver and kidney dysfunction, should be reduced or caution.
2. ischemic heart disease, pituitary and adrenal insufficiency deputy, diarrhea, vomiting and malnutrition in patients with
caution.
3. Elderly patients and children with caution.
4. Use the regular testing of blood glucose, while other hypoglycemic drugs such as insulin sensitizers, α- glucosidase inhibitors
in combination to adjust the dosage.
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Our Company

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

Certifications
Service and Review

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.
 

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