Keywords

• J-147
• Nootropics J-147
• 1146963-51-0

Quick Details

• ProName: High purty Nootropics J-147 CAS NO.114...
• CasNo: 1146963-51-0
• Molecular Formula: C18H17F3N2O2
• Appearance: White Crystal powder
• Application: Medicine，Health Food，Agriculture，Cosme...
• DeliveryTime: 7-10 days
• PackAge: 25kg/drum
• Port: Any port in China
• ProductionCapacity: 100 Metric Ton/Month
• Purity: 99%
• Storage: room temp
• Transportation: by Sea,by land, by air
• LimitNum: 50 Gram
• Related Substances: 0.82%
• Residue on Ignition: 0.73%
• Valid Period: 2 years
• Sample: Available
• Stock: Available
• Brand: JULONG
• COA: Available
• Certificate: ISO/GMP
• Packing: 20&25kgs or 1kg

Superiority

We promise our customer following items:

1.Support product customization:

We can provide OEM&ODM , Because we have a professional design team


2.Reasonable price:
We provide high quality products with competitive price in china,

3.Low moq:
No worry about the low moq, our moq is 1 gram or lower.

3.Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.

4.Super-good quality
We have strict quality control system .Good reputation in Market , And have the Third party test report is available


Pls contact us

If you have any further questions or need a sample,Please do not hesitate to contact us.

Xi'an Julong Bio-Tech Co., Ltd.

Details

J-147 Basic Info:

Product Name：2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide

Other Name:J-147， J147

CAS：1146963-51-0

MF:C18H17F3N2O2

MW:350.3349896

Purity:99%

Appearance:White powder

Specification: 99% by HPLC

What is J-147

J147 was discovered based upon efficacy in multiple cell culture models of age-associated pathologies rather than exclusively amyloid metabolism. It is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer’s disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques, etc.

J-147 is a novel neurotrophic drug for cognitive enhancement and alzheimer's disease. J-147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in alzheimer's disease (ad) transgenic mice. the neurotrophic and memory-enhancing activities of J-147 are associated with an increase in brain derived neurotrophic factor (bdnf) levels and the expression of bdnf responsive proteins, the enhancement of ltp, the preservation of synaptic protein, the reduction of amyloid plaques.

The J147 drug is also reported to address other biological aging factors, such as preventing the leakage of blood from microvessels in mice brains. The development of J147 follows the chemical pharmacological way, contrary to biological ways that exploit e.g. use of bacteriophages.

Enhanced neurogenic activity over J147 in human neural precursor cells has its derivative called CAD-31. CAD-31 is enhancing the use of free fatty acids for energy production by shifting of the metabolic profile of fatty acids toward the production of ketone bodies, a potent source of energy in the brain when glucose levels are low.

The target molecule is a protein called ATP synthase, which is found in the mitochondria. 

1.Improving Memory

2.Improving the brain function

3.Preventing and treating senile dementia

4.Enhancing the learning ability

5.Increasing the attention

6.Relieving the anxiety

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.

Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests

Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.