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Country: China (Mainland)
Business Type:Trading Company
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Tel: +008618049624045
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Tel: +008618049624045
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Province/state: Shaan xi
City: xi'an
Street: Xi'an
MaxCard:
CAS NO.117928-94-6
99%(1-24)box99%(25-99)box99%(100-500)box
Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
3. OEM/ODM Available.
4. Reasonable & competitive price, fast lead time.
5. Sample is available for your evaluation & Formulation development.
6. Faster delivery:Sample order in stock and 3-7 days for bulk production.
7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
8. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Product Details : GLYX-13 /Rapastinel
CAS: 117928-94-6
MF: C18H31N5O6
Sequence: Thr-Pro-Pro-Thr-NH2
Synonyms GLYX 13;L-ThreoninaMide, L-threonyl-L-prolyl-L-prolyl-;GLYX-13 trifluoroacetate;L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate;Thr-Pro-Pro-Thr-NH2 trifluoroacetate;TPPT-amide trifluoroacetate;Rapastinel;GIYX-13
Purity: 99.0%
Appearance: White Powder
Minimum Order Quantity: 1 g
Test Method: HPLC
Rapastinel (GLYX-13) is a NMDA receptor modulator with glycine-site partial agonist properties. It is a robust cognitive enhancer and shows rapid and long-lasting antidepressant properties in both animal models and in humans.
Rapastinel was derived from a monoclonal antibody, B6B21, is a tetrapeptide (threonine-proline-proline-threonine-amide) obtained from amino acid sequence information obtained from sequencing one of the hypervariable regions of the light chain of B6B21. The in-vivo and in-vitro pharmacology of rapastinel was examined.
Benefit:
Rapastinel was found to be a robust cognitive enhancer in a variety of learning and memory paradigms and shows marked antidepressant-like properties in multiple models including the forced swim (Porsolt), learned helplessness and chronic unpredictable stress. Rapastinel's rapid-acting antidepressant properties appear to be mediated by its ability to activate NMDA receptors leading to enhancement in synaptic plasticity processes associated with learning and memory. This is further substantiated by the increase in mature dendritic spines found 24 hrs after rapastinel treatment in both the rat dentate gyrus and layer five of the medial prefrontal cortex. Moreover, ex vivo LTP studies showed that the effects of rapastinel persisted at least two weeks post-dosing.
Function & Application:
1. Enhance mental intelligence;
2. Boost memory and leaning capabilities;
3. Improve brain power to solve problems and protect it from any chemical or physical injury;
4. Enhance motivation level;
5. Enhance the control of cortical/subcortical brain mechanism;
6. Improve sensory perception.
Specification
Item | Specifications | Results |
Assay(HPLC) | 98.0%~102.0% | 99.4% |
Appearance | Off-white fine powder | Complies |
Identification | Positive Reaction | Complies |
Melting point | 224.0~227.0℃ | 224.0~226.0℃ |
Ash | ≤0.1% | 0.08% |
Loss on drying | ≤0.5% | 0.11% |
Residue on ignition | ≤0.1% | 0.06% |
Related substance | ≤1.0% | 0.75% |
Chloride | ≤50ppm | Complies |
Sulphate/Barium salt | ≤60ppm | Complies |
Oxalate | Pass | Complies |
Fe | ≤5ppm | Complies |
As | ≤50ppm | Complies |
Heavy metals | ≤1ppm | Complies |
By Express |
By Air |
By Sea |
||
Suitable for under 50kg |
Suitable for more than 50kg |
Suitable for more than 500kg |
Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
3. OEM/ODM Available.
4. Reasonable & competitive price, fast lead time.
5. Sample is available for your evaluation & Formulation development.
6. Faster delivery:Sample order in stock and 3-7 days for bulk production.
7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
8. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests
Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.