Keywords

• NXL-104
• avibactam
• 1192491-61-4

Quick Details

• ProName: Factory Supply Best Purity 99% API USP...
• CasNo: 1192491-61-4
• Molecular Formula: C18H16O4
• Appearance: White fine powder
• Application: Medicine，Health Food，Agriculture，Cosme...
• DeliveryTime: 7-10 days
• PackAge: 25kg/drum
• Port: Any port in China
• ProductionCapacity: 100 Metric Ton/Month
• Purity: 99%
• Storage: room temp
• Transportation: by Sea,by land, by air
• LimitNum: 1 Kilogram
• Grade: Industrial Grade,Pharma Grade
• Sample: Available
• Stock: Available
• Brand: JULONG
• COA: Available
• Certificate: ISO/GMP
• Packing: 20&25kgs or 1kg

Superiority

We promise our customer following items:

1.Support product customization:

We can provide OEM&ODM , Because we have a professional design team


2.Reasonable price:
We provide high quality products with competitive price in china,

3.Low moq:
No worry about the low moq, our moq is 1 gram or lower.

3.Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.

4.Super-good quality
We have strict quality control system .Good reputation in Market , And have the Third party test report is available


Pls contact us

If you have any further questions or need a sample,Please do not hesitate to contact us.

Xi'an Julong Bio-Tech Co., Ltd.

Details

Product name: avibactam sodium
CAS No:1192491-61-4
Appearance: white powder
Molecular weight: 287.226
Molecular formula:C7H10N3NaO6S
Usage: Avibactam sodium is a covalent and reversible β-lactamase inhibitor, inhibits β-lactamase TEM-1 and CTX-M-15 with IC50 of 8 nM and 5 nM, respectively.
Assay: HPLC; HNRM; LC-MS
[Solubility]:Soluble in ethanol,chloroform,propylene glycol and ethylenediamine. Slightly soluble in diethyl ether. Partly soluble in water.
[Specs] NLT 99%, Food Grade, Pharmaceutical Grade
Capacity: 1000kgs per month
Source: synthetic
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat.
 

What is Avibactam/NXL-104
Avibactam is a non-β-lactam β-lactamase inhibitor developed by Actavis (now Allergan) jointly with AstraZeneca. A new drug application for avibactam in combination with ceftazidime (branded as Avycaz) was approved by the FDA on February 25, 2015, for treating complicated urinary tract (cUTI) and complicated intra-abdominal infections (cIAI) caused by antibiotic resistant-pathogens, including those caused by multi-drug resistant Gram-negative bacterial pathogens.

Avibactam/NXL-104 Benefits

The -lactamase serine nucleophilic attack avibatanamide bond, open loop to form a covalent bond, the enzyme - inhibitor complex, as an enzyme inhibition form, without hydrolysis, and then cyclization to form a lactam ring to get Avibatan Chemicalbook tan. The nucleophilic attack leads to the rate of ring-opening much higher than that of cyclization, resulting in the inhibition of-lactamase. In this process, the structure of Avibatan itself can be restored by the reverse reaction, so it has a long-term inhibitory effect.
It is one of the most promising new -lactamase inhibitors. Compared with the three listed -lactamase inhibitors, they are long-acting and covalently binding to enzyme reversibility, and do not induce -lactamase production.

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.

Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests

Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.