Keywords

• Nootropics Coluracetam
• CAS 135463-81-9 Coluracetam
• Pure Coluracetam 99% Coluracetam

Quick Details

• ProName: Supply Pure Nootropics CAS 135463-81-9...
• CasNo: 135463-81-9
• Molecular Formula: C19H23N3O3
• Appearance: White Powder
• Application: For Bodybuilding Muscle Growth Custom...
• DeliveryTime: Within 3 Days After Payment
• PackAge: Foil Bag / Drum / Bottle
• Port: Shanghai
• ProductionCapacity: 1000 Kilogram/Day
• Purity: 99%
• Storage: Well-Closed, Store in cool and dry are...
• Transportation: Well-Closed, Store in cool and dry are...
• LimitNum: 100 Gram
• Related Substances: ≥98%
• Residue on Ignition: ≤0.1%
• Heavy Metal: ≤10ppm
• Valid Period: 24Months
• Product Name: Coluracetam
• MF: C19H23N3O3
• CAS: 135463-81-9
• Appearance: White Powder
• Grade: Medicine Grade
• Application: Nootropics Product
• Certificate: COA ISO9001 GMP
• Form: Capsules, Liquid, Powder
• Transport Package: Foil Bag / Drum / Bottle
• Purity: 99%
• Shelf Life: 2 Years
• Storage: Cool and Dry Place

Superiority

1. Who are we
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),

Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),

Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates.

4. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement ,

the quality and technical content can reach the advance level in China .

Our products are sold well in China as well as in more than 20 countries.

5. What services can we provide
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian.

6.We promise our customer following items

Support product customization:

We can provide OEM&ODM , Because we have a professional design team.

Reasonable price:
We provide high quality products with competitive price in china,

Low MOQ:
No worry about the low moq, our moq is 1 gram or lower.

Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.

Super-good quality
We have strict quality control system .Good reputation in Market , And have the Third party test report is available.

Details

What's Coluracetam

Coluracetam is a nootropic supplement that is marketed as being able to enhance mental functioning. Nootropics are

a class of supplements that have positive effects on the brain, such as relieving anxiety, enhancing cognitive abilities

and boosting motivation.

Coluracetam (also known as MKC-231) is, as stated earlier, a nootropic supplement that is designed to boost mental

function. It is in the class of nootropics called racetams, which all have similar effects on the brain and all share similar

chemical structures.

Coluracetam is a nootropic agent of the racetam family.It is often touted for its memory boosting effects

and for its effects on manic depression and anxiety. Although Coluracetam is mainly associated with these

benefits, it has also been reported to boost optic properties.It may also have potential use in prevention

and treatment of ischemic retinopathy and retinal and optic nerve injury.

Coluracetam has been shown to reverse the loss of choline acetyltransferase production in the medial

septal nucleus of rats exposed to phencyclidine (PCP), and is considered a potential therapeutic drug

for schizophrenia.

Coluracetam is a racetam that affects acetylcholine, indirectly. Coluracetam is a high affinity choline

uptake enhancer. This activity of the drug increases the efficiency of cholinergic neurons. Most drugs

used to treat Alzheimer's increase acetylcholine, because this neurotransmitter is tightly linked to

learning and memory.
 

Function & Application：

Coluracetam enhances high affinity choline uptake (HACU) which is the rate limiting step of acetylcholine

 (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown

 Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed

 to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive

 effects by changing the choline transporter regulation system.

Memory and Learning

Coluracetam is shown to improve cognitive function and memory in rats, and in theory, the same

results are expected in human beings. A study conducted by BrainCells Inc, showed a memory

improvement in rats who were given substance AF64A (a neuron-specific neurotoxin) for 8 days

along with Coluracetam in 3mg doses. These rats were put through the standardized Morris Water

Maze to mark their ability to get through it, and even up to 72 hours after the last 8mg dose,

they were still able to. Another key finding of this study was that the results were still apparent

3 days after the last dose, even though the serum concentration of Coluracetam was negligible.

Depression and Anxiety

BrainCells Inc, found that a dosage of 240mg (split into three daily doses of 80mg) was useful in

treating major depression co-morbid with GAD (generalized anxiety disorder). However, the

differences were most pronounced in those who didn't find relief in using standard antidepressants.

After one dose, there were no noticeable differences, but after 2 doses at 80mg, 36% had improved

scores during a depression assessment test.

Eyesight

Coluracetam has been associated with optic benefits such as enhanced color vision, recognition

and vividness. Although there isn't any conclusive evidence to support the mechanisms behind this

benefit, experts believe that Coluracetam works in the part of the brain that runs visual processes.

Dosage

Since the study subjects were rats, there aren't any recommended human dosages, but there is

a general guideline for conversion.

In rats, the dosage ranged between 1 mg/kg and 10 mg/kg per day. By using allometric scaling,

the dose becomes 2.9 mg/kg in humans, so the average dose should not exceed 203.5 mg daily for

someone in a typical weight class.

There isn't very much information to indicate toxicity of Coluracetam, although doses given at the

above increments showed no negative side effects. If you haven't used a nootropic before,

you may develop headache after use, which is a common in first time users. By stacking the

Coluracetam with Choline, you'll reduce this risk.

1. Enhance mental intelligence

2. Boost memory and leaning capabilities

3. Improve brain power to solve problems and protect it from any chemical or physical injury

4. Enhance motivation level

5. Enhance the control of cortical/subcortical brain mechanism

6. Improve sensory perception

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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