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Country: China (Mainland)
Business Type:Trading Company
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Province/state: Shaan xi
City: xi'an
Street: Xi'an
MaxCard:
CAS NO.138112-76-2
Powder(50-300)GramPowder(300-500)GramPowder(500-1000)Gram
1. Who are we
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),
Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),
Eastern Europe(00.00%). There are total about 11-50 people in our office.
2. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates.
4. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement ,
the quality and technical content can reach the advance level in China .
Our products are sold well in China as well as in more than 20 countries.
5. What services can we provide
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian.
6.We promise our customer following items
Support product customization:
We can provide OEM&ODM , Because we have a professional design team.
Reasonable price:
We provide high quality products with competitive price in china,
Low MOQ:
No worry about the low moq, our moq is 1 gram or lower.
Good and efficient service,Fast Delivery
Fast respond save client's time, we promise to reply inquiry in 24 hours including holidays and send quotation sheet and other documents in 48 hours.
Super-good quality
We have strict quality control system .Good reputation in Market , And have the Third party test report is available.
What's CAS 138112-76-2 Agomelatine Powder ?
Product name | Agomelatine Powder |
CAS | 138112-76-2 |
MF | C15H17NO2 |
Appearance | White Crystalline Powder |
Assay | 99.5~100.5% |
Agomelatine's unique pharmacology and favorable side effect profile make it a boon for depressed patients, especially those who
have not responded to conventional antidepressants.
Valdoxan tablets contain the active ingredient agomelatine, which is a type of medicine called an antidepr
essant. It is used to treat depression.
Agomelatine acts on the melatonin and serotonin receptors in the brain.
Melatonin is a hormone made by the pineal gland, a structure in the brain. It is normally released soon after it starts to get dark.
The amount produced then increases until about four am, before dropping off again. Melatonin is linked with the control of circadian
rhythms and promoting sleep. It works by acting on melatonin receptors in the brain.
Agomelatine mimics the action of melatonin and helps to re-synchronise the body's circadian rhythms. These include mood, anxiety, appetite,
body temperature and sleep/wake cycles. These circadian rhythms, particularly sleep cycles, are severely disturbed in people with depression.
Agomelatine's main action is to improve the onset and quality of sleep and this in turn has an antidepressant effect.
Agomelatine also helps to improve mood in depression by increasing noradrenaline and dopamine release in the brain. These are natural
chemicals called neurotransmitters that are involved, amongst other things, in regulating mood.
Agomelatine is indicated for the treatment of major depressive episodes in adults.Ten placebo controlled trials have been performed to investigate
the short term efficacy of agomelatine in major depressive disorder. At the end of treatment, significant efficacy was demonstrated in six of the ten
short-term double-blind placebo-controlled studies.Two were considered "failed" trials, as comparators of established efficacy failed to differentiate
from placebo. Efficacy was also observed in more severely depressed patients in all positive placebo-controlled studies.The maintenance of antidepressant
efficacy was demonstrated in a relapse prevention study.
Items |
Specifications |
Results |
Appearance |
White or almost white powder |
Conforms |
Identification |
|
|
A: IR Spectrum |
A: Sample IR spectrum comparable with that of the standard |
Conforms |
B: Chloride |
B: Positive |
Conforms |
pH |
4.0~6.5 |
5.92 |
Impurity E (by TLC) |
NMT0.5% |
<0.5% |
Loss on drying |
NMT0.5% |
0.03% |
Heavy Metals |
NMT20ppm |
<20ppm |
Related Compounds |
Impurity A: NMT1.0% |
ND |
|
Impurity B: NMT0.5% |
ND |
|
Impurity C: NMT0.2% |
0.04% |
|
Impurity D: NMT0.1% |
ND |
|
Any other impurity : NMT1.0% |
0.03% |
|
Total impurity: NMT1.0% |
0.07% |
Residual Solvents |
|
|
Ethanol |
NMT 1000ppm |
314ppm |
Isopropanol |
NMT 1000ppm |
13ppm |
DIchloromethane |
NMT 300ppm |
2ppm |
Assay by HPLC |
97.0%~102.0% |
100.10% |
Conclusion |
The product meets USP Specifications |
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & Formulation development.
7. Faster delivery:Sample order in stock and 3-7 days for bulk production.
8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder
9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Delivery & Payment Terms
Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged
in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials
and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability
of product quality from all aspects. The company has a complete sales service system, the products are exported to countries
all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,
constantly strict requirements, set goals, and implement win-win development.
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