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Home>>Products>>CAS 158563-45-2 Skin Whitening Nonapeptide 1 Melitane Melanostatine Nonapeptide-1

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CAS 158563-45-2 Skin Whitening Nonapeptide 1 Melitane Melanostatine Nonapeptide-1

CAS NO.158563-45-2

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    99%(1-24)Gram99%(25--1)Gram

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  • ProName: CAS 158563-45-2 Skin Whitening Nonapep...
  • CasNo: 158563-45-2
  • Molecular Formula: C61H87N15O9S
  • Appearance: White Powder
  • Application: Cosmetic Grade, Cosmetic Grade
  • DeliveryTime: Have stock can shipping anytime
  • PackAge: 25G~1KG/FOIL BAG
  • Port: Any port in China
  • ProductionCapacity: /
  • Purity: 99%
  • Storage: Cool Dry Place
  • Transportation: By DHL/ By Fedex/ By EMS/By TNT/By Sea...
  • LimitNum: 1 Gram

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Products Description
CAS 158563-45-2 Skin Whitening Nonapeptide 1 Melitane Melanostatine Nonapeptide-1
Product Name
Nonapeptide-1
CAS No
158563-45-2
MF
C61H87N15O9S
MW
1206.50358
pKa
13.32±0.46(Predicted)
Density
1.38±0.1 g/cm3(Predicted)
Introduction:
What is Nonapeptide-1?

Nonapeptide-1, also called Melanostatine-5, is a propriety peptide that was originally developed for its antimicrobial activities.

Animal research has revealed, however, that nonapeptide-1 can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions. Animal models suggest that nonapeptide-1 can reduce synthesis of melanin and help decrease skin pigmentation to a substantial degree.

Nonapeptide-1 was first isolated from the yeast Streptomyces clavifer, but is now produced synthetically through recombinant genetic technology. It was first developed for its antimicrobial activities, but has since been found to be a strong inhibitor of melanin formation laboratory studies of yeast and melanoma (skin cancer) cells .

Nonapeptide-1 consists of the amino acids arginine-lysine-methionine-phenylalanine-proline-tryptophan-valine.
Real Shot
Application &Function:
Research in fungi indicates that nonapeptide-1, at a concentration of 200 ug/mL, is capable of fully inhibiting the synthesis of melanin2. Fungi are used in this particular research because they more closely approximate conditions in human cells, but require fewer resources than animal models. Research in animal models indicates that nonapeptide-1 may effectively reduce pigmentation, after just one application, for up to 28 days at a timev[5]. At 100 micromolar concentration, nonapeptide-1 can inhibit 25-35% of tyrosinase activity in animal models and can reduce the melanin content of melanocytes by 27-43%.

Nonapeptide-1 is of primary research interest for its ability to reduce hyperpigmentation by inhibiting the action of tyrosinase in melanin-producing cells. The ability to regulate melanin production has potential application in a number of conditions, including photodamage of the skin.

Research also suggests that nonapeptide-1 may play a role in the central nervous system where it may act on both dopaminergic receptors and opioid receptors to modify pain signaling as well as behavior. Studies in mice support the idea that nonapeptide-1 may have central actions that affect behavior and pain.
Description
White powder
Complies
Identification
IR
Complies
HPLC
Complies
Heavy metal
≤10ppm
5ppm
Pb
≤3ppm
1.5ppm
Hg
≤0.1ppm
0.05ppm
Cd
≤1ppm
0.2ppm
Loss on drying
≤0.5%
0.12
Residue on lgnition
≤0.1%
0.03
Single impurity
≤0.5%
0.12
Total impurity
≤1.0%
0.29
Total bacteria
≤1000cfu/g
<1000
Yeast and Mould
≤100 cfu/g
<000
E.coli/25g
Absent
Absent
Salmonella/25g
Absent
Absent
Assay
≥99.0%
99.4%
Conclusion
Conforms with USP/EP standards
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1. who are we?
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

4. why should you buy from us not from other suppliers?
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery；
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Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian
Company Profile
Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development
Why Choose Us
1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

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1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 
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