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Xi'an Julong Bio-Tech Co., Ltd.

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Supply CAS 38183-03-8 DHF 7 8-Dihydroxyflavone Powder

CAS NO.38183-03-8

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  • Min.Order: 10 Gram
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  • ProName: Supply CAS 38183-03-8 DHF 7 8-Dihydrox...
  • CasNo: 38183-03-8
  • Molecular Formula: C15H10O4
  • Appearance: White Powder
  • Application: Health Proctect, Health Proctect
  • DeliveryTime: Have stock can shipping anytime
  • PackAge: 25G~1KG/FOIL BAG
  • Port: Any port in China
  • ProductionCapacity: /
  • Purity: 99%
  • Storage: Cool Dry Place
  • Transportation: By DHL/ By Fedex/ By EMS/By TNT/By Sea...
  • LimitNum: 10 Gram

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Products Description
Supply CAS38183-03-8 DHF 7 8-Dihydroxyflavone Powder
Product Name
7,8-DIHYDROXYFLAVONE
CAS No
38183-03-8
MF
C15H10O4
MW
254.24
Melting Point
243-246°C
Boiling Point
494.4±45.0 °C(Predicted)
Density
1.443±0.06 g/cm3(Predicted)
Storage
Store at +4°C
Solubility
DMSO: soluble24mg/mL
Introduction:
7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF). 7,8-DHF is both orally bioavailable and able to penetrate the blood–brain barrier. A prodrug of 7,8-DHF with greatly improved potency and pharmacokinetics, R7, is under development for the treatment of Alzheimer's disease.
Real Shot

Application & Function:

7,8-DHF has demonstrated remarkable therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, Alzheimer's disease, cognitive deficits in schizophrenia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome.

7,8-DHF also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents.

In addition, 7,8-DHF possesses powerful antioxidant activity independent of its actions on the TrkB receptor, and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity.

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1. who are we?
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

4. why should you buy from us not from other suppliers?
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery；
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian
Company Profile
Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development
Why Choose Us
1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 
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